Dr. Bogdan Popescu PhD, MD

Disciplines trained in :	Pathology Neurosciences
Research topics : (associated field)	Multiple Sclerosis (Neurosciences, Mental Health and Addiction) Central Nervous System Inflammatory Diseases (Neurosciences, Mental Health and Addiction) Brain Metabolism (Neurosciences, Mental Health and Addiction) Neuroimmunological Diseases (Neurosciences, Mental Health and Addiction) Neurological Diseases (Neurosciences, Mental Health and Addiction)
Fields of application :	Pathogenesis and Treatment of Diseases

• McLean NA, Popescu BF, Gordon T, Zochodne DW, Verge VM.  Delayed nerve stimulation promotes axon-protective neurofilament phosphorylation, accelerates immune cell clearance and enhances remyelination in vivo in focally demyelinated nerves.  PLoS One. 2014 Oct 13;9(10)
• Guo Y, Lennon VA, Popescu BF, Grouse CK, Topel J, Milone M, Lassmann H, Parisi JE, Pittock SJ, Stefoski D, Balabanov R, Lucchinetti CF.  Autoimmune aquaporin-4 myopathy in neuromyelitis optica spectrum.  JAMA Neurol. 2014 Aug;71(8)
• Robinson CA, Adiele RC, Tham M, Lucchinetti CF, Popescu BF.  Early and widespread injury of astrocytes in the absence of demyelination in acute haemorrhagic leukoencephalitis.  
• Popescu BF, Bunyan RF, Parisi JE, Ransohoff RM, Lucchinetti CF.  A case of multiple sclerosis presenting with inflammatory cortical demyelination.  Neurology. 2011 May 17;76(20):1705-10.Acta Neuropathol Commun. 2014 May 8;2:52.
• Popescu BF, Bunyan RF, Guo Y, Parisi JE, Lennon VA, Lucchinetti CF.  Evidence of aquaporin involvement in human central pontine myelinolysis.  Acta Neuropathol Commun. 2013 Jul 25;1(1):40.
• Wüthrich C, Popescu BF, Gheuens S, Marvi M, Ziman R, Denq SP, Tham M, Norton E, Parisi JE, Dang X, Lucchinetti CF, Koralnik IJ.  Natalizumab-associated progressive multifocal leukoencephalopathy in a patient with multiple sclerosis: a postmortem study.  J Neuropathol Exp Neurol. 2013 Nov;72(11):1043-51. 
• Popescu BF, Lucchinetti CF.  Meningeal and cortical grey matter pathology in multiple sclerosis.  BMC Neurol. 2012 Mar 7;12:11.
• Popescu BF, Lucchinetti CF.  Pathology of demyelinating diseases.  Annu Rev Pathol. 2012;7:185-217
• Popescu BF, Nichol H.  Mapping brain metals to evaluate therapies for neurodegenerative disease.  CNS Neurosci Ther. 2011 Aug;17(4):256-68.
• Bunyan RF, Popescu BF, Carter JL, Caselli RJ, Parisi JE, Lucchinetti CF.  Childhood-onset multiple sclerosis with progressive dementia and pathological cortical demyelination.  Arch Neurol. 2011 Apr;68(4):525-8.
• Popescu BF, Lennon VA, Parisi JE, Howe CL, Weigand SD, Cabrera-Gómez JA, Newell K, Mandler RN, Pittock SJ, Weinshenker BG, Lucchinetti CF.  Neuromyelitis optica unique area postrema lesions: nausea, vomiting, and pathogenic implications.  Neurology. 2011 Apr 5;76(14):1229-37. Epub 2011 Mar 2.
• Popescu BF, Parisi JE, Cabrera-Gómez JA, Newell K, Mandler RN, Pittock SJ, Lennon VA, Weinshenker BG, Lucchinetti CF.  Absence of cortical demyelination in neuromyelitis optica.  Neurology. 2010 Dec 7;75(23):2103-9.
• Apiwattanakul M, Popescu BF, Matiello M, Weinshenker BG, Lucchinetti CF, Lennon VA, McKeon A, Carpenter AF, Miller GM, Pittock SJ.  Intractable vomiting as the initial presentation of neuromyelitis optica.  Ann Neurol. 2010 Nov;68(5):757-61.
• Hopp K, Popescu BF, McCrea RP, Harder SL, Robinson CA, Haacke ME, Rajput AH, Rajput A, Nichol H.  Brain iron detected by SWI high pass filtered phase calibrated with synchrotron X-ray fluorescence.  J Magn Reson Imaging. 2010 Jun;31(6):1346-54.
• Popescu BF, Robinson CA, Chapman LD, Nichol H.  Synchrotron X-ray fluorescence reveals abnormal metal distributions in brain and spinal cord in spinocerebellar ataxia: a case report.  Cerebellum. 2009 Sep;8(3):340-51. Epub 2009 Mar 24.
• Popescu BF, Robinson CA, Rajput A, Rajput AH, Harder SL, Nichol H.  Iron, copper, and zinc distribution of the cerebellum.  Cerebellum. 2009 Jun;8(2):74-9. Epub 2009 Jan 13.
• Popescu BF, George MJ, Bergmann U, Garachtchenko AV, Kelly ME, McCrea RP, Lüning K, Devon RM, George GN, Hanson AD, Harder SM, Chapman LD, Pickering IJ, Nichol H.  Mapping metals in Parkinson's and normal brain using rapid-scanning x-ray fluorescence.  Phys Med Biol. 2009 Feb 7;54(3):651-63. Epub 2009 Jan 9.
• Popescu BF, Belak ZR, Ignatyev K, Ovsenek N, Nichol H.  Asymmetric distribution of metals in the Xenopus laevis oocyte: a synchrotron X-ray fluorescence microprobe study.  Biochem Cell Biol. 2007 Oct;85(5):537-42.
• Popescu BF, Pickering IJ, George GN, Nichol H.  The chemical form of mitochondrial iron in Friedreich's ataxia.  J Inorg Biochem. 2007 Jun;101(6):957-66. Epub 2007 Mar 23.