Dr. Katherine Knox MD, FRCPC

Education

• B Kinesiology, McMaster University
• MD, McMaster University
• FRCPC Physical Medicine & Rehabilitation, University of Saskatchewan

Biography

Dr. Knox is an Associate professor at the University of Saskatchewan, Department of Physical Medicine and Rehabilitation. Her clinical practice includes neuro- rehabilitation services, with a special interest in multiple sclerosis. She obtained her fellowship training in Physical Medicine and Rehabilitation at the University of Saskatchewan (2006), and her Doctor of Medicine and Kinesiology degrees at McMaster University.  She is a primary investigator with the Cameco MS Neuroscience Research Center at the University of Saskatchewan.  Her clinical research focuses on gait, exercise behavior, long term outcomes and quality of life for people with multiple sclerosis.

• Multiple Sclerosis
• General Physiatry
• Spasticity

Publications

• Knox KB, Islam A, Le T, Donkers SJ, Evans C, Lim HJ. Physical activity in multiple sclerosis: Real-world data From Saskatchewan, Canada. Int J MS Care. 2025; 27: 42–49. https://doi.org/10.7224/1537-2073.2024-006
  
  
• Patrick S, Knox KB, Evans C, Levin M, Linassi G, Poliakov I, Rajput A, Donkers SJ. ‘NeuroSask: Active and Connect’ - A virtual chronic disease management program for individuals with a neurological condition. Front Neurol. 2024; 15:1332859. https://doi.org/10.3389/fneur.2024.1332859
  
  
• Knox KB, Nickel D, Donkers SJ, Paul L. Physiotherapist and participant perspectives from a randomized-controlled trial of physiotherapist-supported online vs. paper-based exercise programs for people with moderate to severe multiple sclerosis. Disabil Rehabil. 2022; 45(7): 1147-1153. https://doi.org/1080/09638288.2022.2055159
  
  
• Saini A, Bach K, Poliakov I, Knox KB, Levin MC. Magnetic Resonance Imaging of Spinal Cord Lesions in Patients with Multiple Sclerosis in Saskatchewan, Canada. International Journal of MS Care. 2021; 23(2): 47-51. http://dx.doi.org/10.7224/1537-2073.2019-081
  
  
• Sarpong-Kumankomah S, Knox KB, Kelly ME, Hunter G, Popescu B, Nichol H, Kopciuk K, Ntanda H, Gailer J. Quantification of human plasma metalloproteins in multiple sclerosis, ischemic stroke and healthy controls reveals an association of haptoglobin-hemoglobin complexes with age. PLoS ONE.
  2021; 17(1): e0262160. https://doi.org/10.1371/journal.pone.0262160
  
  
• Sessford JD, Locke SR, Cary MA, Flora PK, Knox K, Brawley LR. Effect of group counseling plus tailored exercise on mobility function in multiple sclerosis. Int J MS Care. 2021; 23(2): 66-72. doi: 10.7224/1537-2073.2019-066
  
  
• Al-Sakran L, Marrie RA, Blackburn D, Knox K, Evans C. Impact of comorbidity on hospitalizations in individuals newly diagnosed with multiple sclerosis: a longitudinal population-based study. Mult Scler Relat Disord. 2020; 40: 101955. doi: 10.1016/j.msard.2020.101955.
  
  
• Al-Sakran L, Marrie RA, Blackburn D, Knox K, Evans C. Predictors of hospitalization in a Canadian MS population: a matched cohort study. Mult Scler Relat Disord. 2020; 40: doi: 10.1016/j.msard.2020.102028.
  
  
• Donkers SJ, Nickel D, Paul L, Wiegers SR, Knox KB. Adherence to physiotherapy-guided web-based exercise for persons living with moderate to severe multiple sclerosis: a randomized-controlled pilot study. Int J MS Care. 2020; 22: 208-214. doi: 10.7224/1537-2073.2019-048.
  
  
• Knox KB, Clay L, Stuart-Kobitz K, Nickel D. Perspectives on walking from people with multiple sclerosis and reactions to video self-observation. Disabil Rehabil. 2020; 42(2): 211-218. doi: 10.1080/09638288.2018.1496154.
  
  
• Knox KB, Saini A, Levin MC. The dilemma of when to stop disease-modifying therapy in multiple sclerosis: a narrative review and Canadian regional reimbursement policies. Int J MS Care. 2020; 22: 75-84. doi: 10.7224/1537-2073.2018-107.
  
  
• Goulding FL, Evans CD, Knox KB, Lim HJ, Levin MC, Donkers SJ. Individualised behaviour change strategies for physical activity in multiple sclerosis (IPAC-MS): protocol for a randomised controlled trial. Trials. 2019; 20: 664. doi: 10.1186/s13063-019-3768-7.
  
  
• Al-Sakran LH, Marrie RA, Blackburn DF, Knox KB, Evans CD. Establishing the incidence and prevalence of multiple sclerosis in Saskatchewan. Can J Neuro Sci. 2018; 45(3): 295-303. doi: 10.1017/cjn.2017.301.
  
  
• Martin N, Traboulsee AL, Machan L, Klass D, Ellchuk T, Zhao Y, Knox KB, Kopriva D, Lala S, Nickel D, Otani R, Rauscher A, Perera WR, Sadovnick AD, Szkup P, Li D. Prevalence of extra-cranial venous narrowing on Magnetic Resonance Venography is similar in people with MS, their siblings, and unrelated healthy controls: a blinded, case-control study. Can Assoc Radiol J. 2017 May; 68(2): 202-209.
  
  
• Hughes KE, Nickel D, Gurney-Dunlop T, Knox KB. Total knee arthroplasty in multiple sclerosis. Arthroplast Today. 2016; 2(3): 117-122. doi: 10.1016/j.artd.2015.12.002.
  
  
• Goodridge D, Rogers M, Klassen L, Jeffery B, Knox K, Rohatinsky N, Linassi G. Access to health and support services: perspectives of people living with a long-term traumatic spinal cord injury in rural and urban areas. Disabil Rehabil. 2015; 37(16): 1401-10. doi: 10.3109/09638288.2014.972593
  
  
• Thorpe LU, Knox K, Jalbert R, Lim JHJ, Nickel D, Hader WJ. Predictors of institutionalization for people with multiple sclerosis. Disabil Health J. 2015; 8: 271-277. doi: 10.1016/j.dhjo.2014.10.002
  
  
• Knox KB, Rohatinsky N, Rogers M, Goodridge D, Linassi G. Access to traumatic spinal cord injury care in Saskatchewan, Canada: A qualitative study on community healthcare provider perspectives. Can J Disabil Stud. 2014; 3(3): 83-103. doi: 10.15353/cjds.v3i3.174
  
  
• Ploughman M, Beaulieu S, Harris C, Hogan S, Manning O, Alderdice P, Fisk JD, Sadovnick D, O’Connor P, Morrow S, Metz LM, Smyth P, Mayo N, Marrie RA, Knox KB, Stefanelli M, Godwin M. The Canadian Survey of Health, Lifestyle and Aging with Multiple Sclerosis: methodology and initial results. BMJ Open. 2014; 4: e005718. doi: 10.1136/bmjopen-2014-005718.