Dr. Saima Alvi MD

Dr. Saima Alvi received her undergraduate, post graduate training in paediatrics and fellowship in pediatric hematology/ Oncology in Pakistan. She has a membership in the discipline of pediatrics from the College of Physicians and Surgeons of Pakistan (FCPS). Dr. Alvi in 2009 came to Vancouver, Canada and completed a 3-years clinical fellowship in Pediatric Hematology/ Oncology and Bone Marrow Transplant from BC- Children Hospital Vancouver. In 2012 she joined The Hospital for Sick Children Toronto, in Hematology/Oncology/ Bone Marrow Transplant that further enhanced the experience. Dr. Alvi then moved to Saskatchewan and worked with Pedaitric Oncology at Saskatchewan Cancer Agency for five years. Since January 2022 she has joined as Pediatric Hematologist/ Oncologist at Jim Pattison Children's Hospital, Saskatoon.

Dr. Alvi’s clinical and research work is focused on childhood malignancies. She is a lead physician for child hood cancer survivorship and late effects program in Saskatchewan. She is also an active member of Children’s Oncology Group (COG)-Long Term Follow-up, Clinical Care Translation Task Force. The main purpose of the task force is to develop and implement guidelines and promoting the health needs of Childhood Cancer Survivors.

Published Articles:

1. Canadian Pediatric Neuro-Oncology Standards of Practice- Frontiers in Oncology, section Pediatric Oncology. Aug 2020. https://doi.org/10.3389/fonc.2020.593192
2. Advances in the diagnosis and management of Haemophagocytic Lympho-histiocytosis: A review of literature. Lymphosign Journal, 5:1–15 (2018)
3. Diagnosis of central nervous system relapse of pediatric acute lymphoblastic leukemia-Impact of routine cytological CSF analysis at the time of intrathecal chemotherapy. Pediatr Blood Cancer. 2014 Dec; 61(12):2215-7
4. Successful Treatment of Acute Lymphoblastic Leukemia in a Child with Trisomy 21 and Complex Congenital Heart Disease with Mechanical Prosthetic Valve Case Reports in Pediatrics Volume 2012, Article ID 193093, doi:10.1155/2012/193093
5. Acute myeloid leukemia in children: Experience at a tertiary care facility of Pakistan. J Pak Med Assoc. Vol. 62, No. 2, February 2012
6. Vaccination Guidelines for Children with Cancer and Hematopoietic Stem Cell Transplantation Living in Resource-Poor Countries. Pediatric Blood & Cancer 2009
7. Kidney tumors in children: A single center experience from a developing country. Turkish Journal of Cancer 133, Volume 39, No. 4, 2009
8. Patent ductus arteriosus: An uncommon cause of tracheobronchial compression in infants. Heart Lung & Circulation 2004;13:426-428

Posters Published:

1. Real-World Experience of Tyrosine Kinase Inhibitors in patients (pt) with Recurrent Bone Tumors (BT): A CanSaRCC (Canadian Sarcoma Research and Clinical Collaboration) Study. ASCO June 2022
2. A real-world experience with long-term elapegademase treatment for adenosine deaminase deficiency. Clinical Immunology Society (CIS) April 2022
3. Association between socioeconomic characteristics and childhood acute lymphoblastic leukemia and survival related outcome- A CYPC-Project oral abstract presentation SIOP, Oct 2020
4. Pediatric Lymphoma: A 10 years’ Experience at a Tertiary Care Hospital, 14th Annual PGME Conference, Aga Khan University, 2009
5. Idiopathic Thrombocytopenia: 7 years’ Experience at a Tertiary Care Hospital. 12th National Health Science Research Assembly Aga Khan University, 2008
6. Acute Myeloid Leukemia in a Tertiary Care Facility of Pakistan. Conference on Childhood Acute Lymphoblastic Leukemia, St. Jude Asia Forum Singapore, 2007
7. AML based therapy in combination with Cis- Retinoic Acid-Case report & review of literature: 3rd International Oncology & Nuclear Medicine Conference & 1st International Conference on Pediatric Oncology, Pakistan July 2005
8. Childhood Cancers: A hospital based epidemiological data of 536 cases. National symposium- current challenges in oncology, Aga Khan University 2002

Guidelines Development:

1. Provincial Febrile Neutropenia Guidelines: Pediatric Hematology/Oncology-Jim Pattison Children's Hospital and Saskatchewan Cancer Agency,2019
2. Supportive Care Guidelines for Blood & Marrow Transplant Unit, Division of Hematology/Oncology/Blood & Marrow Transplant, BC Children Hospital, 2012
3. Designed and updated local protocols for different conditioning regimens for malignant & non-malignant transplants, BC Children Hospital 2011-2012