Dr. Hadi Goubran-Messiha : MBBCh (MD), MSc, PhD, FACP, FRCPEdin

M.B.B.Ch.,  an M.Sc. degree followed by an (M.D) Ph.D. in Internal Medicine from Cairo University, Egypt, where I worked as a professor until I moved to Canada in 2010. Trained as a hematologist at the St. Thomas’ hospital in the U.K. and was elected Fellow of the Royal College of Physicians of Edinburgh and Fellow of the American College of physicians.

*Joined the Saskatoon Cancer Centre as a hematologist and the College of Medicine of the University of Saskatchewan in 2010. Appointed as a regional adviser to the Royal College of Physicians of Edinburgh in Eastern Canada.

*Shared in the writing of Davidson’s clinical cases and sits on the international advisory board of the textbook “Davidson’s Principles and Practice of Medicine” since 2010 and served as a reviewer and co-editor, and associate editor for few hematology journals.

*Co-Editor of “Precision Anticoagulation Medicine: A practical guide.” Springer 2020

*Co-Editor of “Paraproteinemia and Related Disorders.” Springer Nature, 2021

*Published 56 peer-reviewed articles and two book chapters with nearly 2500 citations in the last five years.

Graduate teaching of hematology and undergraduate internal medicine teaching of skills II, II and IV

• Hematology
• platelets disorders
• rare blood diseases

Blood-derived biomaterials, viral inactivation of biologicals, platelet cancer interactions and platelet microparticles and the microbiome in hematology. 

• Jancy Johnson, Yu-Wen Wu, Chantelle Blyth, Gregor Lichtfuss, Hadi Goubran, & Thierry Burnouf Prospective Therapeutic Applications of Platelet Extracellular Vesicles. Trends in Biotechnology 2020 Nov 4:S0167-7799(20)30268-7. DOI: 10.1016/j.tibtech.2020.10.004.0
• Yu-Wen Wu, Chun A Changou, Cheng-Chain Huang, LongSheng Lu, Hadi A Goubran, Thierry    
• Burnouf. Clinical-grade cryopreserved doxorubicin-loaded platelets: role of cancer cells and platelet Extracellular activation loop. J Biomed Sci 2020 March 23;27(1):45 DOI: 10.1186/12929-020-006332 
• Burnouf T, Burnouf PA, Wu YW, Lu Y.L. and Goubran H. Circulatory cell-mediated nanotherapeutic approaches in disease targeting. Drug Discovery Today – 2018 May;23(5):934-943.
• Goubran H, Seghatchian J, Ragab G, and Burnouf T. The Microbiome and transfusion in cancer patients. Transfusion Apheresis Science – Theme Transfusion and Cancer – June 2017; 56: 330-335 https://doi.org/10.1016/j.transci.2017.05.023
• Goubran H, Sheridan D, Burnouf T and Seghatchian. Transfusion-related immune modulation and cancer. Transfusion Apheresis Science – Theme Transfusion and Cancer – 2017; 56: 336-340  https://doi.org/10.1016/j.transci.2017.05.019
• Stakiw J, Bosch M and Goubran. A Closer look at the bone marrow microenvironment in multiple myeloma. Tumour and Microenvironment. www.tmeresearch.org. DOI:10.4103/2395-7182.203049 
• Yu-Wen Wu, Goubran H, Seghatchian J, Burnouf T. Smart blood cells- and microvesicles- based Trojan horse drug delivery: Merging blood transfusion and biomedical engineering expertise in the field of nanomedicine. Transfusion Apheresis Science 2016 Apr; 54(2):309-18.
• Goubran H, Sabry W,Kotb R, Seghatchian J, Burnouf T, Platelet microparticles and cancer: An intimate cross-talk, Transfusion and Apheresis Science 2015 Oct; 53(2):168-72
• Burnouf T, Chou ML, Goubran H, Cognasse F, Garaud O and Seghatchian J. An overview of the role of microparticles/microvesicles in blood components: Are they clinically beneficial or harmful? Transfusion and Apheresis Science 2015 Oct; 53(2):137-45
• Goubran H, Kotb R, Stakiw J, Emara M, Thierry Burnouf. Regulation of Tumor Growth and Metastasis; the role of Tumor Microenvironment. Cancer Growth and Metastasis. June 2, 2014, 7: 9-18
• Goubran HA and Burnouf T, Radosevich M & El-Ekiaby M. The platelet-cancer loop.
• The European Journal of Internal Medicine. , 2013; 24: 393-400
• Burnouf T, Goubran H, Radosevich M Human blood-derived biomaterials and platelet growth factors in regenerative medicine – Blood Reviews, 2013; 27:77-89
• Burnouf T, M. Radosevich, H.A. Goubran, & H. Willkommen; Place of Nanofiltration
• in the Viral Safety of Biologicals, Current Nanoscience 2005(1): 3:189-209 (Review Editorial)
• Goubran HA, Burnouf T, Radosevich M; Virucidal Heat-Treatment of single plasma units: A potential approach for developing countries. Haemophilia 2000 (6), 597-604
• Burnouf T, Goubran HA, Radosevich M; Application of Bioaffinity Technology in 
• Therapeutic Extracorporeal Plasmapheresis and Large-scale Fractionation of Human Plasma.  
• Journal of Chromatography B, 1998; 715: 65-80
  
• Radosevich M, Goubran HA, Burnouf T., Fibrin Sealant: Scientific Rationale, Production Methods, Properties and Current Clinical Use; Vox Sanguinis 1997; 72:133-143