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Mellor, P., Marshall, J. D. S., Ruan, X., Whitecross, D. E., Ross, R. L., Knowles, M. A., Moore S. A. and Anderson, D. H. (2018) Patient-derived mutations within the N-terminal domains of p85alpha impact PTEN or Rab5 binding and regulation. Sci. Rep. 8, 7108 (PCCF acknowledgement)

Aamudalapalli, H.B., Bertwistle, D., Palmer, D.R.J. and Sanders, D.A.R. (2018) Myo-Inositol dehydrogenase and scyllo-inositol dehydrogenase from Lactobacillus casei BL23 bind their substrates in very different orientations. BBA - Proteins and Proteomics, 1866, 1115-1124

Ghavidel, A., Baxi, K., Prusinkiewicz, M., Swan, C., Belak, Z.R., Eskiw, C.H., Carvalho, C.E. and Harkness, T.A. (2018) Rapid nuclear exclusion of Hcm1 in aging Saccharomyces cerevisiae leads to vacuolar alkalization and replicative senescence. G3 (Bethesda), 8(5), 1579-1592

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Wang, Y., Chen, X., Hu, Y., Zhu, G., White, A. P. and Köster, W. (2018) Evolution and sequence diversity of FhuA in Salmonella and Escherichia. Infect. Immun. 86(11):e00573-18

Toosi, B. M., El Zawily, A., Truitt, L., Shannon, M., Allonby, O., Babu, M., DeCoteau, J., Mousseau, D., Ali, M., Freywald, T., Gall, A., Vizeacoumar, F. S., Kirzinger, M. W., Geyer, C. R.Anderson, D. H., Kim, T., Welm, A. L., Siegel, P., Vizeacoumar, F. J., Kusalik, A. and Freywald, A. (2018) EPHB6 receptor augments both development and drug sensitivity of triple-negative breast cancer tumours.  Oncogene. 37(30), 4073-4093

Ulaganathan, T., Helbert, W., Kopel, M., Banin, E. and Cygler, M. (2018) Structure-function analyses of a PL24 family ulvan lyase reveal key features and suggest its catalytic mechanism. J. Biol. Chem., 293, 4026-4036

Grishin, A.M., Barber, K.R., Gu, R.X., Tieleman, D.P., Shaw, G.S. and Cygler, M. (2018) Regulation of Shigella effector kinase OspG through modulation of its dynamic properties. J. Mol. Biol., 430, 2096-2112

Ulaganathan, T., Banin, E., Helbert, W. and Cygler, M. (2018) Structural and functional characterization of PL28 family ulvan lyase NLR48 from Nonlabens ulvanivorans. J. Biol. Chem., 293, 4026-4036

Beyrakhova, K., Li, L., Xu, C., Gagarinova, A. and Cygler, M. (2018). Legionella pneumophila effector Lem4 is a membrane-associated protein tyrosine phosphatase. J. Biol. Chem., 293, 13044-13058.

Xu, A., Zhang, L., Yuan, J., Babikr, F., Freywald, A., Chibbar, R., Moser, M., Zhang, W., Zhang, B., Fu, Z. and Xiang, J. (2018) TLR9 agonist enhances radiofrequency ablation-induced CTL responses, leading to the potent inhibition of primary tumor growth and lung metastasis. Cell Mol Immunol. 16(10), 820-832

Nyarko, J.N.K., Quartey, M.O., Heistad, R.M., Pennington, P.R., Poon, L.J., Knudsen, K.J., Allonby, O., El Zawily, A.M., Freywald, A., Rauw, G., Baker, G.B. and Mousseau, D.D. (2018) Glycosylation states of pre- and post-synaptic markers of 5-ht neurons differ with sex and 5-httlpr genotype in cortical autopsy samples. Front Neurosci. 12, 545-61

Jing, A., Vizeacoumar, F.S., Parameswaran, S., Haave, B., Cunningham, C.E., Wu, Y., Arnold, R., Bonham, K., Freywald, A., Han, J. and Vizeacoumar, F.J. (2018) Expression-based analyses indicate a central role for hypoxia in driving tumor plasticity through microenvironment remodeling and chromosomal instability. NPJ System Biology and Application. 4, 38-48

Xie, Y., Wu, J., Xu, A., Ahmeqd, S., Sami, A., Chibbar, R., Freywald, A., Zheng, C. and Xiang, J. (2018) Heterologous human/rat HER2-specific exosome-targeted T cell vaccine stimulates potent humoral and CTL responses leading to enhanced circumvention of HER2 tolerance in double transgenic HLA-A2/HER2 mice. Vaccine. 18, 30151-8

Tan, X., Xu, A., Zhao, T., Zhao, Q., Zhang, J., Fan, C., Deng, Y., Freywald, A., Genth, H. and Xiang, J. (2018) Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK pathways. Scientific Reports. 8: 3769-3781

Parameswaran, S., Kundapur, D., Vizeacoumar, F.S., Freywald, A., Uppalapati, M. and Vizeacoumar, F.J. (2018) A road map to personalizing targeted cancer therapies using synthetic lethal approaches. Trends in Cancer. 5(1):11-29

Reis, J.M., Xu, X., McDonald, S., Woloschuk, R.M., Jaikaran, A.S.I., Vizeacoumar, F.S., Woolley, G.A., and Uppalapati, M. (2018) Discovering Selective Binders for Photoswitchable Proteins Using Phage Display, ACS Synth Biol 7, 2355-2364

Sharma, P., Gangola, M.P., Huang, C., Kutcher, H.R., Ganeshan, S. and Chibbar, R.N.            (2018) Single Nucleotide Polymorphisms in B-Genome Specific UDP-Glucosyl Transferases Associated with Fusarium Head Blight Resistance and Reduced Deoxynivalenol Accumulation in Wheat Grain. Phytopathology, 108(1), 124-132

Karunaratne, N.D., Abbott, D.A., Hucl, P.J., Chibbar, R.N., Pozniak, C.J. and Classen, H.L. (2018) Starch digestibility and apparent metabolizable energy of western Canadian wheat market classes in broiler chickens. Poult Sci. 97(8), 2818-2828

Belak, Z.R., Ovsenek, N. and Eskiw, C.H. (2018) Conserved RNA binding activity of a Yin-Yang 1 homologue in the ova of the purple sea urchin Strongylocentrotus purpuratus. Sci Rep. 8(1):8061

MacKay, K., Kusalik, A. and Eskiw, C.H. (2018) GrapHi-C: graph-based visualization of Hi-C datasets. BMC Res Notes, 11(1):418

Tyagi, M., Cheema, M.S., Dryhurst, D., Eskiw, C.H, Ausió, J. (2018) Metformin alters H2A.Z dynamics and regulates androgen dependent prostate cancer progression.  Oncotarget. 2018 Dec 11;9(97):37054-37068.

Belak, Z.R., Harkness, T. and Eskiw, C.H. (2018) A rapid, high-throughput method for determining chronological lifespan in budding yeast. J Biol Methods, 5(4), e106

El-Sayed, A., Bernhard, W., Barreto, K., Gonzalez, C., Hill, W., Pastushok, L., Fonge, H. and Geyer, C.R. (2018) Evaluation of antibody fragment properties for near-infrared fluorescence imaging of HER3-positive cancer xenografts. Theranostics, 8(17), 4856-4869.

Solomon, V.R., Gonzalez, C., Alizadeh, E., Bernhard, W., Hartimath, S.V., Barreto, K., Geyer, C.R. and Fonge, H. (2018) 99mTc(CO)3+ labeled domain I/II-specific anti-EGFR (scFv)2 antibody fragment for imaging EGFR expression. Eur J Med Chem. 157, 437-446

Alam, M.K., Zheng, L., Liu, R., Papagerakis, S., Papagerakis, P. and Geyer, C.R. (2018) Synthetic antigen-binding fragments (Fabs) against S. mutans and S. sobrinus inhibit caries formation.  Sci Rep., 8(1), 10173

Chekol, R., Solomon, V.R., Alizadeh, E., Bernhard, W., Fisher, D., Hill, W., Barreto, K., DeCoteau, J.F., Parada, A.C., Geyer, C.R. and Fonge, H. (2018) 89Zr-nimotuzumab for immunoPET imaging of epidermal growth factor receptor I. Oncotarget., 9(24), 17117-17132

Al-Dulaymi, M., Michel, D., Chitanda, J.M., El-Aneed, A., Verrall, R.E., Grochulski, P. and Badea, I. (2018) Molecular engineering as an approach To modulate gene delivery efficiency of peptide-modified Gemini surfactants. Bioconjug Chem., 29(10):3293-3308

Harkness, T.A.A. (2018) Activating the Anaphase Promoting Complex to Enhance Genomic Stability and Prolong Lifespan. Int J Mol Sci., 19(7), 1888

Hu, Z., Xia, B., Postnikoff, S.D., Shen, Z.J., Tomoiaga, A.S., Harkness, T.A., Seol, J.H., Li, W., Chen, K. and Tyler, J.K. (2018) Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan. Elife. 7, e35551

Jois, S., Chan, Y.B., Fernandez, M.P. and Leung, A.K. (2018) Characterization of the Sexually Dimorphic fruitless Neurons That Regulate Copulation Duration. Front Physiol., 9:780

Goel, R.K., Meyer, M., Paczkowska, M., Reimand, J., Vizeacoumar, F., Vizeacoumar, F.J., Lam, T.T. and Lukong, K,E. (2018) Global phosphoproteomic analysis identifies SRMS-regulated secondary signaling intermediates. Proteome Sci., 16:16.

Zhao, T., Li, R., Tan, X., Zhang, J., Fan, C., Zhao, Q., Deng, Y., Xu, A., Lukong, K.E., Genth, H. and Xiang, J. (2018) Simulated Microgravity Reduces Focal Adhesions and Alters Cytoskeleton and Nuclear Positioning Leading to Enhanced Apoptosis via Suppressing FAK/RhoA-Mediated mTORC1/NF-κB and ERK1/2 Pathways. Int J Mol Sci., 19(7), 1994

Goel, R.K., Paczkowska, M., Reimand, J., Napper, S., Lukong, K.E. (2018) Phosphoproteomics Analysis Identifies Novel Candidate Substrates of the Nonreceptor Tyrosine Kinase, Src-related Kinase Lacking C-terminal Regulatory Tyrosine and N-terminal Myristoylation Sites (SRMS). Mol Cell Proteomics, 17(5), 925-947

da Silva, C.S., de Cássia Gonçalves de Lima, R., Elekofehinti, O.O., Ogunbolude, Y., Duarte, A.E., Rocha, J.B.T., Alencar de Menezes, I.R., Barros, L.M., Tsopmo, A., Lukong, K.E. and Kamdem, J.P. (2018) Caffeine-supplemented diet modulates oxidative stress markers and improves locomotor behavior in the lobster cockroach Nauphoeta cinerea. Chem Biol Interact., 282, 77-84

Vidhyasagar, V., He, Y., Guo, M., Talwar, T., Singh, R.S., Yadav, M., Katselis, G., Vizeacoumar, F.J., Lukong, K.E. and Wu, Y. (2018) Biochemical characterization of INTS3 and C9ORF80, two subunits of hNABP1/2 heterotrimeric complex in nucleic acid binding. Biochem J., 475(1), 45-60

Luo, Y., Javed, M.A., Deneer, H. and Chen, X. (2018) Nutrient depletion-induced production of tri-acylated glycerophospholipids in Acinetobacter radioresistens. Sci Rep., 8(1), 7470

Luo Y, Javed MA, Deneer H. (2018) Comparative study on nutrient depletion-induced lipidome adaptations in Staphylococcus haemolyticus and Staphylococcus epidermidis. Sci Rep., 8(1), 2356

Silva-Junior, E.A., Ruzzini, A.C., Paludo, C.R., Nascimento, F.S., Currie, C.R., Clardy, J. and Pupo, M,T. (2018) Pyrazines from bacteria and ants: convergent chemistry within an ecological niche. Sci Rep., 8(1), 2595

McFie, P.J., Banman, S.L. and Stone, S.J. (2018) Diacylglycerol acyltransferase-2 contains a c-terminal sequence that interacts with lipid droplets. Biochim Biophys Acta Mol Cell Biol Lipids, 1863(9), 1068-1081

Bharti, S.K., Sommers, J.A., Awate, S., Bellani, M.A., Khan, I., Bradley, L., King, G.A., Seol, Y., Vidhyasagar, V., Wu, Y., Abe, T., Kobayashi, K., Shin-Ya, K., Kitao, H., Wold, M.S., Branzei, D., Neuman, K.C. and Brosh, R.M. Jr. (2018) A minimal threshold of FANCJ helicase activity is required for its response to replication stress or double-strand break repair. Nucleic Acids Res., 46(12), 6238-6256

Almousa, A.A., Meurens, F., Krol, E.S. and Alcorn, J. (2018) Linoorbitides and enterolactone mitigate inflammation-induced oxidative stress and loss of intestinal epithelial barrier integrity. Immunopharmacol, 64, 42-51

Duff, W., Haskey, N., Potter, G., Alcorn, J., Hunter, P. and Fowler, S. (2018) Non-pharmacological therapies for inflammatory bowel disease: Recommendations for self-care and physician guidance. World J Gastroenterol., 24(28), 3055-3070

Carrozzo, M.V., Alcorn, J. and Ambros, B. (2018) Effects of two fentanyl constant rate infusions on thermal thresholds and plasma fentanyl concentrations in awake cats. Vet Anaesth Analg., 45(6), 831-838

Reithmeier, D., Tang-Wai, R., Seifert, B., Lyon, A.W., Alcorn, J., Acton, B., Corley, S., Prosser-Loose, E., Mousseau, D.D., Lim, H.J., Tellez-Zenteno, J., Huh, L., Leung, E., Carmant, L. and Huntsman, R.J. (2018) The protocol for the Cannabidiol in children with refractory epileptic encephalopathy (CARE-E) study: a phase 1 dosage escalation study. BMC Pediatr., 18(1), 221

James Huntsman, R., Tang-Wai, R., Acton, B., Alcorn, J., Lyon, W.A., Mousseau, D.D., Seifert, B., Laprairie, R., Prosser-Loose, E., Hanuš, O.L. (2018) Cannabis for the treatment of paediatric epilepsy? An update for Canadian paediatricians. Paediatr Child Health., 23(6), 368-373

Di, Y., De Silva, F., Krol, E.S. and Alcorn, J. (2018) Flaxseed Lignans Enhance the Cytotoxicity of Chemotherapeutic Agents against Breast Cancer Cell Lines MDA-MB-231 and SKBR3. Nutr Cancer., 70(2), 306-315

Almousa, A.A., Morris, M., Fowler, S., Jones, J. and Alcorn, J. (2018) Elevation of serum pyruvate kinase M2 (PKM2) in IBD and its relationship to IBD indices. Clin Biochem., 53:19-24

Mohammadzadeh, N., Follack, T.B., Love, R.P., Stewart, K., Sanche, S. and Chelico, L. (2018) Polymorphisms of the cytidine deaminase APOBEC3F have different HIV-1 restriction efficiencies. Virology, 527, 21-31

Feng, Y., Wong, L., Morse, M., Rouzina, I., Williams, M.C. and Chelico, L. (2018) RNA-Mediated Dimerization of the Human Deoxycytidine Deaminase APOBEC3H Influences Enzyme Activity and Interaction with Nucleic Acids. J Mol Biol., 430(24), 4891-4907

Adolph, M.B., Love, R.P. and Chelico, L. (2018) Biochemical Basis of APOBEC3 Deoxycytidine Deaminase Activity on Diverse DNA Substrates. ACS Infect Dis., 4(3), 224-238