Picture of Dr. Sidney Hayes

Dr. Sidney Hayes Faculty, Biochemistry, Microbiology & Immunology

Research Areas

  • Molecular genetics, Microbial physiology

About Dr. Sidney Hayes

Areas of Expertise

Molecular Genetics, Microbial Physiology

Research Interests

Bacteriophage genetics: regulation of chromosomal rearrangements, mutagenic mechanism, developmental regulation immunity/exclusion, replication initiation.

Selected Publications

Hayes S, Wang W, Rajamanickam K, Chu A, Banerjee A, and Hayes C.  Lambda gpP-DnaB Helicase Sequestration and gpP-RpoB Associated Effects: On Screens for Auxotrophs, Selection for RifR, Toxicity, Mutagenicity, Plasmid Curing.  Viruses. 2016, 8(6),172;doi:10.3390/v8060172

Hayes S, Erker C, Horbay MA, Marciniuk K, Wang W, Hayes C.  Phage Lambda P protein: trans-activation, inhibition phenotypes and their suppression.  Viruses. 2013 Feb 6;5(2):619-53

Hayes S, Horbay MA, Hayes C (2012) A CI-Independent Form of Replicative Inhibition: Turn Off of Early Replication of Bacteriophage Lambda. PLoS ONE 7(5): e36498. doi:10.1371/journal.pone.0036498

Hayes S, Gamage LN, Hayes C. Dual expression system for assembling phage lambda display particle (LDP) vaccine to porcine Circovirus 2 (PCV2). Vaccine. 2010 Sep 24;28(41):6789-99. Epub 2010 Aug 1.

Gamage LN, Ellis J, Hayes S. Immunogenicity of bacteriophage lambda particles displaying porcine Circovirus 2 (PCV2) capsid protein epitopes. Vaccine. 2009 Nov 5;27(47):6595-604. Epub 2009 Aug 25.

Hayes S, Asai K, Chu AM, Hayes C. NinR- and red-mediated phage-prophage marker rescue recombination in Escherichia coli: recovery of a nonhomologous immlambda DNA segment by infecting lambdaimm434 phages.Genetics. 2005 Aug;170(4):1485-99. Epub 2005 Jun 14.

Hayes S, Slavcev RA. Polarity within pM and pE promoted phage lambda cI-rexA-rexB transcription and its suppression. Can J Microbiol. 2005 Jan;51(1):37-49.

Slavcev RA, Hayes SOver-expression of rexA nullifies T4rII exclusion in Escherichia coli K(lambda) lysogens. Can J Microbiol. 2004 Feb;50(2):133-6.

Slavcev RA, Hayes SBlocking the T4 lysis inhibition phenotype. Gene. 2003 Dec 4;321:163-71.

Slavcev RA, Bull HJ, Hayes SBacteriophage lambda repressor allelic modulation of the Rex exclusion phenotype.Can J Microbiol. 2003 Mar;49(3):225-9.

Slavcev RA, Hayes SStationary phase-like properties of the bacteriophage lambda Rex exclusion phenotype. Mol Genet Genomics. 2003 Apr;269(1):40-8. Epub 2003 Mar 5.

Dimmock JR, Zello GA, Vashishtha SC, Hayes SJ, Mutalik S, Kumar S, Venkatesh M, Udupa N. A toxicological evaluation of 2-dimethylaminomethyl-1-phenyl-2-propen-1-one hydrochloride. Pharmazie. 2003 Feb;58(2):136-9.

Slavcev RA, Hayes SRex-centric mutualism. J Bacteriol. 2002 Feb;184(3):857-8.