Picture of Dr. Helen Nichol

Dr. Helen Nichol PhD Faculty, Anatomy & Cell Biology

We use the synchrotron as well as cell and molecular biology techniques to examine the role of metals in stroke, MS and common neurodegenerative diseases.

Research Areas

  • Applications of synchrotron technology to medicine

Selected Publications

Mariam Alaverdashvili, Sally Caine, Xue Li, Mark J. Hackett, Michael P. Bradley, Helen Nichol, Phyllis G. Paterson (2018)  Protein-Energy Malnutrition Exacerbates Stroke-Induced Forelimb Abnormalities and Dampens Neuroinflammation. Translational Stroke Research 9(6), 622-630

Colby A. Nadeau, Kristen Dietrich, Cassandra M. Wilkinson, Andrew M. Crawford,  Graham N. George, Helen Nichol (2018) Prolonged Blood-Brain Barrier Injury Occurs After Experimental Intracerebral Hemorrhage and Is Not Acutely Associated with Additional Bleeding. Translational Stroke Research, published online June 2018.

Williamson MR, Dietrich K, Hackett MJ, Caine S, Nadeau CA, Aziz JR, Nichol H, Paterson PG, Colbourne F. Rehabilitation Augments Hematoma Clearance and Attenuates Oxidative Injury and Ion Dyshomeostasis After Brain Hemorrhage. STROKE. 2017 Jan;48(1):195-203. Epub 2016 Nov 29.

Wowk S, Fagan KJ, Ma Y, Nichol H, Colbourne F. Examining potential side effects of therapeutic hypothermia in experimental intracerebral hemorrhage. J Cereb Blood Flow Metab. 2017 Aug;37(8):2975-2986. Epub 2016 Jan 1.

Hackett MJ, Smith S, Caine S, Nichol H, George G, Pickering I, Paterson P. Novel bio-spectroscopic imaging reveals disturbed protein homeostasis and thiol redox with protein aggregation prior to hippocampal CA1 pyramidal neuron death induced by global brain ischemia in the rat. Free Radical Biology & Medicine. 2015;89:806-818.

Gagnon K, Caine S, Samadi N, Martinson M, Melanie L, Alcorn J, Chapman LD, Belev G, Nichol H. Design and testing of a live mouse restraint for synchrotron computed tomography imaging. J. Synchrotron Radiation. 2015;22.(5.):1297-1300.